key,value
build,"""GRCh38"""
columns,"[""SCREEN_V4_Classes"",""SCREEN_V4_Accessions"",""SCREEN_V4_Overlap_Count""]"
counts,"{""variants"":6475578,""overlapping_variants"":1410047,""element_overlaps"":1410108,""multiple_element_variants"":61}"
format,"""evo2ved.screen_variant_annotations.v1"""
freeze,"""2026-09-10"""
limitation,"""Coordinate overlap does not establish tissue-specific activity, a target gene or a functional effect. The legacy ENCODE label is a separate annotation."""
overlap_rule,"""GRCh38 REF footprint [Position-1, Position-1+len(Reference_Allele)) overlaps original SCREEN BED [start0,end0)."""
primary_input_sha256,"""fd23b30dd71642184478c42fb9280241e575ca6d0f3365972897f70cc92c551e"""
release,"""Registry V4 / GRCh38"""
screen_class_records,"{""CA-CTCF"":126034,""CA-H3K4me3"":79246,""CA-TF"":26102,""CA"":245985,""PLS"":47532,""TF"":105286,""dELS"":1469205,""pELS"":249464}"
screen_records,2348854
screen_records_digest_order,"""id; compact JSON row + newline; all eight original columns"""
screen_records_sha256,"""c92cd09cf6190dfa266cce0646b1a922fcc975115aac7a47490cf5e49d45d144"""
source_registry,"{""source_id"":""screen"",""name"":""SCREEN Registry V4"",""release"":""Registry V4 / GRCh38"",""freeze"":""2026-09-10"",""logical_files_json"":""[\""SCREEN_Registry_V4_GRCh38/GRCh38-cCREs.CA-CTCF.bed\"",\""SCREEN_Registry_V4_GRCh38/GRCh38-cCREs.CA-H3K4me3.bed\"",\""SCREEN_Registry_V4_GRCh38/GRCh38-cCREs.CA-TF.bed\"",\""SCREEN_Registry_V4_GRCh38/GRCh38-cCREs.CA.bed\"",\""SCREEN_Registry_V4_GRCh38/GRCh38-cCREs.PLS.bed\"",\""SCREEN_Registry_V4_GRCh38/GRCh38-cCREs.TF.bed\"",\""SCREEN_Registry_V4_GRCh38/GRCh38-cCREs.dELS.bed\"",\""SCREEN_Registry_V4_GRCh38/GRCh38-cCREs.pELS.bed\"",\""SCREEN_Registry_V4_GRCh38/README.md\""]"",""metadata_json"":""{\""record_unit\"":\""unique cCRE element\"",\""workplan_ids\"":[\""H1\""],\""source_url\"":\""https://screen.wenglab.org/downloads\"",\""display_fields\"":[[\""accession\"",\""cCRE accession\""],[\""eh38d_id\"",\""Original registry ID (EH38D/EH38F)\""],[\""class\"",\""SCREEN class\""],[\""start0\"",\""BED start (0-based)\""],[\""end0\"",\""BED end (exclusive)\""],[\""overlap_bp\"",\""Overlap bp\""]],\""notes\"":\""Coordinate annotation; not tissue-specific activity or confirmed target-gene evidence. Kept separate from legacy Coding/Intronic labels.\"",\""identity_check\"":\""Eight original BED classes; positive half-open intervals; globally unique EH38E accessions; exact integer spatial index.\"",\""original_source_status\"":\""original_download_location_documented_in_package_readme\"",\""original_inputs\"":[{\""file\"":\""GRCh38-cCREs.CA.bed\"",\""url\"":\""https://downloads.wenglab.org/Registry-V4/GRCh38-cCREs.CA.bed\""},{\""file\"":\""GRCh38-cCREs.CA-CTCF.bed\"",\""url\"":\""https://downloads.wenglab.org/Registry-V4/GRCh38-cCREs.CA-CTCF.bed\""},{\""file\"":\""GRCh38-cCREs.CA-H3K4me3.bed\"",\""url\"":\""https://downloads.wenglab.org/Registry-V4/GRCh38-cCREs.CA-H3K4me3.bed\""},{\""file\"":\""GRCh38-cCREs.CA-TF.bed\"",\""url\"":\""https://downloads.wenglab.org/Registry-V4/GRCh38-cCREs.CA-TF.bed\""},{\""file\"":\""GRCh38-cCREs.PLS.bed\"",\""url\"":\""https://downloads.wenglab.org/Registry-V4/GRCh38-cCREs.PLS.bed\""},{\""file\"":\""GRCh38-cCREs.TF.bed\"",\""url\"":\""https://downloads.wenglab.org/Registry-V4/GRCh38-cCREs.TF.bed\""},{\""file\"":\""GRCh38-cCREs.dELS.bed\"",\""url\"":\""https://downloads.wenglab.org/Registry-V4/GRCh38-cCREs.dELS.bed\""},{\""file\"":\""GRCh38-cCREs.pELS.bed\"",\""url\"":\""https://downloads.wenglab.org/Registry-V4/GRCh38-cCREs.pELS.bed\""}],\""original_input_scope\"":\""Eight human Registry V4 class files, GRCh38; no tissue-specific activity or gene-link data.\"",\""provenance_documents\"":[\""SCREEN_Registry_V4_GRCh38/README.md\""]}"",""record_count"":2348854}"
variant_class_counts,"{""CA-CTCF"":71248,""CA"":163106,""pELS"":131966,""TF"":70093,""CA-H3K4me3"":52860,""dELS"":875014,""PLS"":28434,""CA-TF"":17338}"