Choose one GWAS study, derive gene windows, then explore scored regions and exact variants.
The independent Variant Analysis, Region/Region Set Analysis and Trait Analysis modules remain available at any time.
1. Select one study
Search the original phenotype name, study ID, category or cohort. Disease, protein, metabolite, imaging and other traits retain their original labels.
2. Derive a gene region set
Genes enter when their TSS is within ±1 Mb of a seed (inclusive). Each window is the complete gene body ±500 kb, clipped to GRCh38 chromosome boundaries. Overlapping or adjacent windows form a union for analysis. A nearby gene is an exploratory candidate, not an assigned causal gene.
Select a study to begin.
GWAS source · original associations and derived windows
rsID-only seeds describe a position. Same-position alternate alleles are not assigned a shared allele-specific effect. Multi-position rsIDs are excluded. Seeds without a nearby gene are retained in the export; no replacement window is invented.
Source, reference and parameters
Original seed → gene links
3. Evo2VED · analyze the region union
Every scored allele in the union is eligible, including variants without a stored GWAS P value. Six-configuration comparisons use their common valid sample.
4. Choose a gene window
Select a merged region to see its genes. Opening a gene uses its own gene-body ±500 kb window. Counts include all scored alleles in each window; overlapping windows can share variants.