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Evo2 Variant Effect Database
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Region views Gene / single region Region set / BED GWAS association tracks

Region / Gene — Evo2 scores, source-specific evidence and original research results for a gene or genomic window.

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Spearman ρ among all six configurations uses their common set of variants with finite scores. Per-configuration coverage is preserved in the analysis export.

|Evo2 Δ| (log scale) along the locus; colour = the sign of Δ (red: ALT less surprising than REF; green: ALT more surprising). Height is |Δ|, which is what ranks variants. The strongest labelled rsIDs use a separate band and leader lines above the point cloud. Drag to zoom.

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Δ = log P(ALT) − log P(REF). Panels A/B show |Δ| stratified by region / consequence with group mean ± SEM, two reference lines (selected-set mean, genome-wide mean), and one-sample tests (t or Wilcoxon; BH-adjusted). Research use only. With no query, this page shows the APOE locus by default.

Evidence by data source

Choose a source before searching. Original variant records and original molecular models use separate analysis units and counts.

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